Sacrifice of animals and serum collection At the end of the experimental period the rats in each study groups were fasted overnight and sacrificed under anesthesia while blood collection was done by cardiac puncture. Groups I to VI were administered graded doses of 0, 400, 800, 1200, 1600, and 2000 mg/kg bw, respectively. Highly Cited. Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments. The crude extract was subjected to preliminary phytochemical analysis in order to confirm the various classes of secondary metabolites present using standard procedure, … Abstract The methanolic bark extract of Khaya senegalensis was investigated for its effects on the cardiovascular system. 2006;26:2397-2406. Source of isolates. Dank einer Verbindung aus Resveratrol, Hyaluronsäure und Veganer Kollagen Booster korrigiert die Hautverdichtende Kaschmir Creme Falten, strafft die Haut und steigert die Spannkraft wieder. Limonoids and Triterpenoids from Khaya senegalensis, J. Nat. The phenolics-rich fraction of Khaya senegalensis A. Juss (Meliaceae) stem bark extract (pfks) has been previously reported to possess potent antitrypanosomal activity at 300 mg/kg body weight (bw) but could not completely prevent disease-induced anemia and organ damage in addition to being slightly hepatotoxic at the same dose. Hayanolides from African mahogany Khaya senegalensis (Meliaceae): A revision. The phytochemical constituents of stem bark extracts of Khaya senegalensis were isolated and analyzed using Gas Chromatography-Mass Spectrometry (GC-MS). Khaya senegalensis is a species of tree in the Meliaceae family that is native to Africa. Environment . Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of … After sacrifice, 2-4ml of blood was collected from each rats and placed in specific sterile bottles (plain … The phytochemical constituents of stem bark extracts of Khaya senegalensis were isolated and analyzed using Gas Chromatography-Mass Spectrometry (GC-MS). Canadian Journal of Pure and Applied Sciences, 3 (3): 925-928. Evidence from scientific studies have indicated that Khaya senegalensis extract contain significant amount of phenolic compounds [24]. Papers overview. 2008. Khaya senegalensis bark extract (KSBE) has been hypothesized to contain inhibitors of the cyclooxygenase-2 (COX-2) gene and to be useful in the prevention and treatment of colorectal cancer. 3, Aug. 2015 660 dried in a ventilated-convention oven at 45°C for 24h, then ground in a hammer mill (Culatti Polymix, Germany) endowed with a sieve of pore size 250 µm. From the bark of this tree, ... (271), yet this compound exhibited only weak antifeedant activity. DOI: 10.1021/np1000158. 2004) and cattle ticks (Boophilus decoloratus) (Choudhury and Boshe 2013). No Data, Some Concern . 2076 Jimeta- Yola, Adamawa State, Nigeria. Known as: KHAYA SENEGALENSIS BARK, Khaya Senegalensis Extract National Institutes of Health Create Alert. K. senegalensis also contain glycosides, steriods, terpenoids and anthraquinones [44] [45]. KHAYA SENEGALENSIS BARK EXTRACT can be found in 1 … No Data, Some Concern . 300 g of the powder sample was soaked in 750 mL of distilled water for 48 h. Thereafter the solution was filtered and the filtrate was evaporated in an oven at 40°C to produce a dark brown residue. Extraction procedure: The dry stem bark of Khaya senegalensis were cut into small pieces and pulverized into fine powder using a grinding machine. Zhang H, Tan J, Vanderveer D, Wang X, Wargovich MJ, Chen FK. Common names include African mahogany, dry zone mahogany, Gambia mahogany, khaya wood, Senegal mahogany, cailcedrat, acajou, djalla, and bois rouge. The subchronic effect of aqueous stem bark extract of Khaya senegalensis on some biochemical, haematological, and histopathological parameters of rats was investigated. Cancer . Therefore, the effects of a combined administration of … Prod, 73 (4): 669-674. The rats were divided into six groups of five rats per group. KHAYA SENEGALENSIS BARK EXTRACT . Asthma/Respiratory . 2DEPARTMENT OF PHARMACOLOGY, FACULTY OF BASIC MEDICAL SCIENCES, COLLEGE OF HEALTH SCIENCES, … The bark is in high demand for medicinal purposes and can be found on many local markets. In order to assess the potency of aqueous stem bark extract of Khaya senegalensis (KS) against liver diseases, serum aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP) were assayed in rats treated with two (2) different doses of the extract after the induction of liver damage in the rats using carbon tetrachloride, CCl4. Anti-inflammatory activity was demonstrated to be significant in the inhibition of cyclooxygenase (COX) enzymes, in particular COX-2 (9,18). Keywords: Khaya senegalensis, rabbit, performance, blood parameters, carcass INTRODUCTION Medicinal plants, which refer to the whole plant, leaves, flowers and plant ex- tracts, can enhance animal performance. Seeds are harvested from natural stands and traded worldwide, e.g. Semantic Scholar uses AI to extract papers important to this topic. Developmental & Reproductive Toxicity . Celestine et al. 2Biological Sciences Department, Federal University of Technology, Yola, P.M.B. [22] … 27 Printed in Nigeria Increased liver alkaline phosphatase and aminotransferase activities following administration of ethanolic extract of Khaya senegalensis stem bark to rats Musa T. YAKUBU*a, Oluwatope cJ.ADEBAYOb, Evans C. EGWIM and Victor B. OWOYELEb aDepartment of Biochemistry, University of Ilorin, Ilorin, Nigeria. Chemopreventive effects of Khaya senegalensis bark extract on human colorectal cancer. bD ep artm nofP h ys il gdB c ,C M U v I N. (2010). In vitro preliminary study of free radical scavenging … The subchronic effect of aqueous stem bark extract of Khaya senegalensis on some biochemical, haematological, and histopathological parameters of rats was investigated. A shade-dried stem bark of K. senegalensis was extracted using methanol and water as solvents. The inhibitory effect of Khaya senegalensis bark and oil extracts was carried out in the Medical Laboratory of Microbiology Department, Modibbo Adama University of Technology, Yola Adamawa State, Nigeria. Anticancer Research. Khaya senegalensis, also from the Meliaceae, is used as a popular traditional medicine in Africa. 12 No. Probably the wood of Khaya senegalensis is occasionally mixed with the wood of other Khaya spp. 2009;70:294-299. administered 4000mg/kg of Khaya senegalensis bark extract. No Data, Some Concern . Plant collection, authentication and extraction. Optimization of total polyphenols and tannins content during extraction of Khaya tea (Khaya senegalensis): Effect of water volume, temperature and infusion time ISSN : 2028-9324 Vol. No Data, Some Concern . Skin Allergies & Irritation . Kigelia Africana Leaf Extract Inhaltsstoff für Kosmetik. Bark extracts have been reported to have good anticancer 6,13,14 and anti-inflammatory properties 6 are good immunostimulants 11 and are insect deterrents. In-vitro control trial using aqueous and ethanol extracts of Khaya senegalensis stem bark extract proved effective against the pathogens as there was a signiicant reduction in mycelial growth compared to control, however there was no signiicant variation between the aqueous and ethanol stem bark extracts (Table 1). Lompo M, Dubois J, Guissou IP. This effect had been comparable to the effect of insulin 2,5IU solution used like reference substance in this experimentation. Phytochemical screening and evaluation of stem bark extract of Khaya senegalensis (Meliaceae) on methicillin resistant Staphyloccocus aureus. EXTRACT OF KHAYA SENEGALENSIS, KHAYA SENEGALENSIS BARK EXTRACT, and KHAYA SENEGALENSIS EXTRACT. 2008. Saponin, Flavonoids, alkaloid, and tannin were found in Water and ethanol extract of stem (bark) and leaf of Khaya senegalensis [6]. Groups I to VI were administered graded doses of 0, 400, 800, 1200, 1600, and 2000 mg/kg bw, respectively. That is what this type of work is started. OF Khaya ivorensis STEM BARK EXTRACTS ON WOODS ... Limonoids isolated from K. senegalensis fruits, and seed oil exhibited strong biological activity against the plant pathogenic fungus Botrytis cinerea Pers (Abdelgaleil et al. Aims & Objective: The ... Khaya senegalensis barks total extracts had reduced hepatic liberation of glucose. 8 K. senegalensis bark extracts have potential in the treatment of diabetes and have been reported to have anti-hyperglycemic activity comparable to glibenclamide. Methodology: Hyperlipidemia was induced in rats via feeding on high lipid diet (HLD) for 6 weeks. Kigelia Africana Bark Extract Inhaltsstoff für Kosmetik. The rats were divided into six groups of five rats per group. aqueous extract of Khaya senegalensis stem-bark might have significantly reduces depletion of the endogenous antioxidant reverse as part of its therapeutic action. In order to assess the potency of aqueous stem bark extract of Khaya senegalensis (KS) against liver diseases, serum aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP) were assayed in rats treated with two (2) different doses of the extract after the induction of liver damage in the rats using carbon tetrachloride, CCl 4. Kochia Scoparia Fruit Powder Inhaltsstoff für Kosmetik. Aim: To investigate the effect of oral administration of Aqueous-methanol stem bark extract of Khaya senegalensis and its solvents (hexane, chloroform and ethyl acetate) extracts on lipid profile of hyperlipidemic rats. Cancer . The extract of Khaya senegalensisis used in the traditional treatment of gastric ulcers (Dalziel, 1956).The crude methanol extract of the stem-bark of Khaya senegalensis has been shown to possess anti-ulcer activity against ethanol induced gastric ulceration in rats (Suleiman et al., 2013). 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